Biological macromolecules, such as proteins and nucleic acids, are the basic building blocks of life. Their dynamic motions and interactions are essential for all biological processes, including respiration, digestion and muscle motion. The dynamics and interactions of biomolecules need to be understood in order to solve many important problems in key technologies such as pharmaceutics, polymer science and nanotechnology. Currently, experiments cannot resolve structural detail without significantly influencing the dynamics. Computer simulations, on the other hand, can only reproduce short-lived motions due to the computational effort.
The scientific goals of the computational molecular biology group at FU Berlin are: